Single Gene Diss, Chromosome Abnormalities, Multifactorial Diss

deoxyribonucleic acid Ab radiation diagramities that Manifest as DissYour name HereSTATEMENT OF THE PROBLEMThe purpose is to yield the fol brokening questionsUsing our intimacy of the elementtic code , transcription and adaptation explain how a bingle agent dis may hook from a renewing . Cite an example of a superstar ing inflammationient dis , explaining what gene has been transmuteed , how this walk outs the product of this gene , and how this may affect the health of the individual carrying the mutation . If possible enunciate what the specific mutation isUsing your knowledge of replication , meiosis , and binding , explain how a chromosome mental defectiveness may nobble in the offspring of both well individuals . Cite an example of a chromosome abnormality , explaining what chromosome or chromosomal segme nt is missing or duplicated , and how this may affect the health of the individual carrying the abnormalityNot all wound atomic number 18 slowly to explain , but some (such as breast genus Cancer colon cancer , type 2 diabetes ) tend to hand more often within acc rosyited families . Using your knowledge of biotechnology , explain how specific DNA abnormalities can be used to determine a mortal`s chances of evolution some diseases , and how this knowledge may continue the development of the diseaseANSWERSSingle gene dis may tog up from a mutationSingle gene dis may arise from mutation . The process of transcription and rendition can be disrupted by these forms of mutations . These mutations include virtuoso base rally that suppress termination of protein translation , alter patterns of mRNA splicing during transcription (Garden 2002 . Another mutation is bingle base omission that definitely changes the outcome of mRNA transcription or the protein entailment of transl ation . One example of a single stall dis i! s the reaping hook cell disease . In people with sickle cell disease at least(prenominal) one of the beta hemoglobin subunits in hemoglobin is replaced with hemoglobin S (Genetic Home extension service , 2007 . Sickle red course cells become distorted forming a cell that looks like a sickle .

This distorted red blood cell is uneffective to ripey transfer oxygen and may sometimes encumber up in the blood vessels . The low oxygen might and short life span of sickled red blood cells reachs genus Anemia to the person afflicted with these heritable dis . This is a form of single base substitution where a norma l amino acid (valine ) is replaced by another one (glutamineChromosome abnormality may arise in the offspring of two healthy individualsThree mechanisms contribute to genetic variation during meiosis and grooming . These are independent miscellany of chromosomes , crossing over and random fertilization . Within these triple processes is window for chromosome dis to occur . Meiotic nondisjunction , the ill fortune of the chromosomes to disjoin and keep to to opposite poles , in either the prime(prenominal) or second meiotic division is the major cause of chromosomal abnormalities (Tissot Kaufman , 2007 . This includes trisomy , which is the mien of 3 chromosomes instead of 2 . cut down syndrome , or trisomy 21 , is the classic example of a homophile disease caused by autosomal nondisjunction where some , but not all , touched individuals do survive (Tissot Kaufman , 2007 . Trisomy 21...If you want to get a full essay, order it on our website: OrderCustomPaper.com

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