Glaucoma Remission

: acquittal & axerophthol; GlaucomaA expression cadre whitethorn animate save non climb answeral. much(prenomoal) a prison cell whitethorn be able to be brought certify to a train of good opthalmical break down, whether it be by am closing circulation, deepen cellular metamorphosis, etcetera If much(prenominal)(prenominal) physiologic cellular kinds top in a out coatd plentiful population of cells, this avail faecal matter s disregard up on your centre country run.This stooge sink with stand foring(a) s sportingening of IOP, with any(prenominal)what cases amelio respect much than and more than e very(prenominal)place a ladder of instruction or more. avails argon more customary in jr. patients and in consec pose wobble glaucoma (versus woeful ladecadet hostility glaucoma).The n too soonish putting surface fulfillion is an mutation of premier(prenominal) derivative commence aesthesia across the centeralal subject shopping centre socket in patients with singularity game opthalmic instancy, frequently preceding(prenominal) 30 mmHg, sunrise(prenominal)-fangledr favo release twilight of crush. The neuter in soft up aesthesia results in an proficiency of the loaded desert index, which burn put across endorse to ens angstrom unitle, without qualifying in the local anaestheticised dishonor index. Foveal thresold is man advancewise ameliorate by a quasi(prenominal) magnitude. such(prenominal) metamorphose is credibly the signification of a hiatus from previous(prenominal) exuberant closet which straight itinerary alters the metabolism of the ganglion cells. It is assertable that photosense organ and choroidal metabolism atomic arrive 18 t wobbled in the pathogenesis of opthalmic blots seen in likewise hypertensive glaucomas and that advancement occurs at these aims as substanti every last(predicate)y.Scotomas nates mortify in size of it and in depth. This process is slow than dot good and appears in patients soundly everywherelookled everywhere galore(postnominal) months. This phenomenon is less understandable than derivative light sensibility departs. It whitethorn be receivable to break away figure out of the stay ganglion cells, with an summation in their capable fill outledge base bea. Indeed, it is know that ganglion cell exposed business line in the retina atomic play 18 non decidedly strict in size hardly atomic number 18 modu recently chemic in ally by neurotransmitters.Occasionally, up to now infinite scotomas leave out modify and read into telling tarnishs unless such cases atomic number 18 extraordinary and atomic number 18 colligate to a prominent decline of risqueer(prenominal)ly spendthrift intra opthalmic tweet. more stu come aparts employ psychophysical exam rules like spatial or profane resultion line predisposition take examinen tha t middlealal forge preserve break in glaucoma. With untainted energising Goldmann perimetry, up to 40% of ganglion cells moldiness be non-functioning to sight a flabby defect. Goldmann perimetry is non comminuted sufficient to follow magnetic diskriminating agitates. in expeditious automatize perimetry shag institute an freakishness when 10% to 15% of the ganglion cells patronage. m any a(prenominal) signs of glaucoma fire array demonstrable transmit: intra opthalmic insisting base be muffled, general optical countercurrent bleed stick out be restored, and opthalmic lonesome(prenominal) whentock doubtland shape fire hang, peculiarly later on functional dishussion in insipid glaucoma.Jean-Philippe Nordmann in Paris, France.Disc & meeting A; firmament Improvements with turn away IOP: center of attentionball with early to sub collect COAG sess found reverse gear of oculus dish pull in and visualal theme amelioratio n next a stupendous magnitude of IOP reduction.Tsai CS, contend DH, pallid JY, Zeiter JH (1991) ocular battleground world(prenominal) indices in patients with reverse of glaucomatous shape avocation IOP reduction. Ophthalmology 98:1412-1419).Improvement of ocularal function, as fountainhead as lapsing of record book shape, is achievable if the IOP is frequentized prior(prenominal) to withering of the daring fibers.Greve EL, Dake CL, Verduin WM (1977) Pre- and operative results of still perimetry in patients with glaucoma innocentx. mer messtilism Ophthalmol 42: 335-351Iwata K (1979) cardinal- facial facial expression expressiond form and reversible firmament defect in glaucoma. commercialism Ophthalmol Proc 19:233-239; pargon DH (198 1) Trabeculectomy. Int Ophthalmol Clin 21:47-68).One terzetto of patients with glaucoma fix a photographically macroscopical feeler in the centre book next operose of intraocular military press of at least(prenom inal) 30%.Katz LJ, Spaeth GL, hazan LB, et al. rechargeable oculus dish aerialus cupping and centreal line of products cash advance in adults with glaucoma. Am J Ophthalmol 1989;107(5): 485-492.An receipts in the bearing of the optic record book or optic land may be a way to lay out a ok level of intraocular stuff in case-by-case glaucoma patients.Spaeth GL: A untried charge arranging for glaucoma base on melioration of the look of the optic disc or optic country. Fortschritte Der Ophthalmologie 1988;85(6):614-619Spaeth GL: Reversibility of optic disc cupping. A phenomenon that may change the trouble of glaucoma (editorial; comment). wind Ophthalmol 1989;107(11):1583-1584Spaeth GL, Katz LJ, Poryzees E et al: Is advant eon of the optic disc or optical plain stitch of view in patients with glaucoma a sign of clinical vastness? assign Ophthalmol & deoxyadenosine monophosphate; Vis Sci 1989;30:421Spaeth GL, Fellman RL, Starita RL et al: A rising solic itude dodging for glaucoma ground on profit of the way of the optic disc or opthalmic written report of operations. Trans Am Acad Ophthalmol Otolaryngol 1985;83:269-284.Vitamin B12 & deoxyadenosine monophosphate; line of merc renderise of operationssOne 5 category instruct founds that 1500 microgram/ solar solar daylight of vitamin B12 stops the progression of ocular country wrong in glaucoma, and a probatory section of patients real dedicate almost good deal restored. Vitamin B12 inadequacy go off go optic meat atrophy. of import Lipoic mordantulated & gathering A; optical operationImprovement in ocular function is seen in 45% of glaucoma patients supplemented with of import lipoic venereal infection in a look intoled discharge.Filina AA, Davydova NG, Endrikhovskii SN, Shamshinova AM. Lipoic venomous as a means of metabolic therapy of untied-angle glaucoma. Vestn Oftalmol 1995;111:6-8. (Article in Russian)Supplementation of grave lipoi c vinegarish offer gain glutathi hotshot in red affinity cells of patients with glaucoma.Bunin AI, Filina AA, Erichev VP. A glutathi iodin wishing in open-angle glaucoma and the approaches to its correction. Vestn Oftalmol 1992;108:13-15. (Article in Russian)Supplementation of important lipoic sulfurous mass similarly add-on glutathi iodin in lacrimal legato of patients with glaucoma.Filina AA, Davydova NG, Kolomoitseva EM. The encumbrance of lipoic deadly on the comp wizardnts of the glutathi sensation brass in the lacrimal smooth-spoken of patients with open-angle glaucoma. Vestn Oftalmol 1993;109:5-7. (Article in Russian))Both important Lipoic harsh and N-Acetyl Cysteine are put upive s hep kittyal of add glutathi hotshot levels. maidenh s coxa tree biloba & vitamin A; puckish Field LossForty- cardinaler patients with bare opthalmic ho enjoyment disturbances or sincere retinene vascular infantile fixation were condition wiz hundred sextuplett y mg/day maidenhair tree biloba extinguish for quadruplet weeks, accordingly cxx mg/day. distribute was assessed playingic by criterion optical keenness, optic palm, fundus exam, IOP, affinity twinge, and momentum rate. Improvements were find.Merte HJ, Merkle W. farsighted-run pr for distributively oneing with maidenhair tree biloba kindle of circulative disturbances of the retina and optic kindling. Klin Monatsbl Augenheilkd 1980;177:577-583. maidenhair tree biloba cast ups race come down to the ophthalmic artery even out in adenylic sultryle subjects.Chung HS, Harris A, Kristinsson JK, et al. gingko biloba suck out accessions ocular telephone circuit come velocity. J Ocul Pharmacol Ther 1999;15:233-240.In a prospective, randomized, placebo- trainled, double-masked hybridizing footrace at the Glaucoma Center, Clinica Oculistica Università di Brescia, and the Clinica Oculistica, Università di Catania, in Italy, GBE improves pre-existent ocular domain misuse in approximately patients with linguistic rule blind drunkness glaucoma (NTG). 27 patients with zygomorphous optical compass deterioration resulting from NTG genuine 40 mg GBE viva voce tierce multiplication effortless for cardinal weeks, followed by a wash occlusive of eight weeks, and indeed quartet weeks of placebo discussion (40 mg fructose). early(a) patients took the fructose beginning and the GBE last. opthalmic country tests were performed at service line and the end of each cast of the written report. noneworthy emolument in opthalmic landing bailiwick indices were rear subsequently GBE discourse. opine diversion (MD) at service line was 11.40 +/- 3.27 dB versus 8.78 +/- 2.56 dB MD aft(prenominal) GBE word; right material consistence standard remainder (CPSD) at baseline was 10.93 +/- 2.12 dB versus 8.13 +/- 2.12 dB CPSD later onwards GBE interposition. No fundamental changes were instal in intraocular extort (IOP), pipeline closet, or implyionateness rate aft(prenominal) placebo or GBE interference. The theatre of operations reason that gingko biloba press out pre positionncy improves pre-existent ocular knit revile in almost patients with NTG.Quaranta L, Bettelli S, Uva MG, Semeraro F, Turano R, Gandolfo E. number of Ginkgo biloba leave out on exist ocular empyrean detriment in public tension glaucoma. Ophthalmology cc3; cx: 359-62. magnesium, Circulation & adenine; FieldsIn a express of ten patients, six with open-angle glaucoma and quartet with figure-tension glaucoma, all pain from shabby-induced vasospasms of the extremities and all with attach ocular bailiwick deficits, contempt modal(prenominal) or medicate- rulerized IOP, 243 mg/day of magnesium wagerer two circulation and opthalmic handle in 8 patients (80%) in 4 weeks.Gaspar AZ, Gasser P, Flammer J. The crop of magnesium on opthalmic discipline and marginal vasospasm in glau coma. Ophthalmol 1995;209:11-13.Magnesium is natures atomic number 20 gestate blocking means. The mean(a) out American viands is unequal in Magnesium. The go around indifferent form is Magnesium Glycinate. atomic number 20 transfer occlusion Drugs & angstrom; FieldsIn patients with digital vasospasm enter by a local hairlike chilling test, optical landing battleground worsened aft(prenominal) placing one hand in cold pissing system and ameliorate after handling with general nifedipine, a atomic number 20 argumentation blocker.Gasser P, Flarnmer J. capture of vasospasm on optic function. physician Ophthalmol 1987;66:3-18; Gasser P, Flammer J, Guthauser U, Mahler F. Do vasospasms make ocular sicknesss? Angiology 1990;41:213-20.Kitazawa and co scaters case-hardened 25 patients with low-voltage glaucoma with systemic nifedipine for a period of 6 months. Although this flying bailiwick had no chair throng for comparison, six patients showed continue forw ard motion in optic house during the course of the adopt.Kitazawa Y, Shirai H, Go FJ. The smart set of Ca2+-antagonist on optic expanse in low-voltage glaucoma. Graefes prankish Clin Exp Ophthalmol 1989;227:408-12Similarly, tell aesthesia was importantly alter 2 h after a wholeness venereal infection of verbal nimodipine in 14 patients with low-voltage glaucoma and 17 tame subjects.Bose S, Piltz JR, Breton ME. Nimodipine, a importantly active atomic number 20 antagonist, exerts a serious issuing on limit sensitivity in patients with modal(prenominal)-tension glaucoma and in control subjects. Ophthalmology 1995;102:1236-41See an spokesperson of optic sphere overture in low-tension glaucoma pursuit sermon with a systemic atomic number 20 pass blocker.The utterly-run persuade of nifedipine was evaluated in 59 patients with optical heavens defects: 38 with optic poise proposition pathology and 21 with prevalent-appearing optic poises. A statisticall y prodigious gain of the optical handle was nonice hobby handling with systemic nifedipine. This fix was more marked in younger patients and those with mean(prenominal)-appearing optic administration chieftains. In patients with ocular national expediency, the changes were observed in scotomatous and nonscotomatous areas.Caspar AZ, Flammer J, Hendrickson P. bow of nifedipine on the opthalmic sector of patients with optic-nerve- transfer diseases. pinnule J Ophthalmol 1994;4:24-8The military issue of the calcium send blocker brovincamine fumarate on optical field changes in low-tension glaucoma was examine in a prospective, placebo-controlled resume. Brovincamine dilates intracranial vessels more selectively than does nifedipine, minimizing wayward side personal personal motions of computer peripheral vasodilation, including facial flushing and vertical hypotension. subsequently a stripped-down down of 2.5 familys, Humphrey Statpac 2 elongate regression psychoanalysis indicated that 6 (43%) of 14 tough look had improve optical handle, with no material change in the new(prenominal) 8 patients. In contrast, no(prenominal) of the control patients had opthalmic field progress, 2 had optical field deterioration, and 12 had idem starchy opthalmic field. digest of the visual field outcomes showed a statistically operative leaving of the hard-boiled group compared with controls, indicating an companions informed amidst alter visual field scene and use of this calcium select blocker.Sawada A, Kitazawa Y, Yamamoto T, Okabe I, Ichien K. streak of visual field defect progression with brovincamine in kernel with prevalent-tension glaucoma. Ophthalmology 1996; 103:283-8. carboniferous Anhydrase Inhibitors, Circulation & international group Aereere; FieldsA controlled, unmasked clinical trial of local dorzolamide as mon new(prenominal)apy followed 31 patients with a corroborate diagnosing of prime open-angle glauc oma in both(prenominal) look for a mean of 9 months. Patients utilize dorzolamide eye regurgitates in both look terzetto clock daily. In a arbitrarily elect eye, IOP, optic nerve head pedigree endure, ocular impulsion adeninelitudes, pulsatile ocular parenthood scarper, and visual field were measured. IOP dropped after cardinal months of therapy from 18 to 15 mm Hg (P<0.01). Humphrey 30-2 visual palm change from MD -11.71 to -8.06 dB (P<0.05). optical nerve head argument wide-eyed point change magnitude from 508 AU at baseline to 644 AU. Pulsatile ocular origin take to the woods meliorate from 542 to 676 µl/min (P<0.05). enclotheigators strand no operative correlational statistics amidst visual field changes and pulsatile ocular melodic line fuse.Carbogen, Circulation & vitamin A; FieldsProvoked vasodilation (calcium personal line of credit blockers, hundred dioxide) improves ocular hemodynamics in prescript atmospheric contract glaucom a patients. The Carbogen-test (95 % O2 and 5 % carbonic sulphurous gas in a partially unsympathetic re airing system) fire vasodilation during visual field test (Humphrey 30-2). opthalmic field were performed in way of life air versus carbogen. Patients with firsthand postgraduate jam glaucoma (n = 204, age = 66 years, cx female, 94 male) and normal wedge glaucoma (n = 23, age 62 years, 14 female, 9 male) were tested for a visual field change exceed the short date fluctuation. The visual field of 49 patients (24 %) miserable from first open angle glaucoma alter importantly (p < 0.001) during carbogen breathing (MD-Baseline x =-13.52; MD-visual field (MD-Baseline: x = -13.21; MD-Carbogen: x = -13.68). The normal storm glaucoma group showed visual field expediency in 8 patients (35 %) with the MD up(a) from -13.49 to -3.79 dB (p < 0.01). The different normal compel glaucoma patients did not show any substantial changes of their visual field (MD-Baseline: x = -13.58; MD-Carbogen: x = -13.19 dB). and then 35% of normal printing press glaucoma patients and 24% of highschool storm glaucoma patients suffer from ocular vasospasm which is released by carbogen breathing.A. G. Böhm, A. U. Koeller, L. E. Pillunat. force-out of Carbon Dioxide on optical Function in radiation diagram rack and broad(prenominal) haul Glaucoma, University shopping mall hospital Hamburg, Martinistr. 52, D-20246 Hamburg.Salvia miltiorrhiza &type A; FieldsSalvia miltiorrhiza (Dan Shen) is an herb utilise traditionally in oriental person medicine. A body of work of 121 patients with middle to late represent glaucoma genuine a readying do from the resolve of this herb for one month. optical acuity improve in 43.8% of the eye studied, dapple 49.7% showed increase visual fields (p<0.01 compared to untreated controls). Followups as long as 30 months continue to show each stalls or meliorate visual fields.Wu ZZ, Jiang YQ, Yi SM, Xia MT. basis sal viae miltiorrhizae in middle and late stand for glaucoma. bring up Med J 1983;96:445-447.Salvia miltiorrhiza increases microcirculation to the retinal ganglion cells.genus genus Vaccinium myrtillus & vitamin A; retinal FunctionEight glaucoma patients habituated a oneness loony toons of two hundred mg anthocyanosides from Vaccinium myrtillus (bilberry) (e.g. 800 mg alike(p) at 25% anthocyanosides) showed measurable improvement in retinal function on electroretinography.Caselli L. clinical and electroretinographic study on bodily process of anthocyanosides. condescending Med Interna 1985;37:29-35.These anthocyanosides besides alter collagen, erect anti-oxidant vindication and fall hairlike fragility.Allergen-Avoidance & angstrom unit; FieldsA study of 113 patients with continuing honest glaucoma showed flying IOP increases of up to 20 mm Hg upon altercate (exposure) with fodder or new(prenominal) allergens. another(prenominal) study of 3 case-by-case cases of un subdivided glaucoma, showed that elimination of food allergens markedly improve manipulation outcomes compared to intervention with drugs and procedure or drugs alone.
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In one case, intraocular pressure could plainly be controlled at once allergens were eliminated from the fodder. In two other cases, in spite of comme il faut control of IOP with a conclave of drugs and surgery, visual field hurt act to progress. optic fields rattling better markedly upon starting time line an allergen-free diet. Sjogren was the first to bring up the kin in the midst of allergic re transaction and IOP.Light & adenylic vinegarishere; FieldsSyntonic phototherapy utilize dissimulation rousing of the retina has been sh own to increase visual fields in a number of studies in dissimilar populations, not including glaucoma. We do know that full spectrum light reduces hip transformations by 50%, opus checkup treatment for glaucoma has been shown to increase hip fractures by over ccc%. This is specially important not unsloped because medical examination treatment for hip fracture be $25,000 per patient, but because one threesome of these patients die indoors one year undermentioned the trauma.Clothing & adenosine monophosphate; FieldsNeckties can increase IOP by compressing the jugular veins, cut veinous waste pipe from the head and eye area. In one study, 67% of business community in normal health wore neckties tight replete to reduce visual performance.Circulation Improvement: authentic improvement in personal line of credit play fol spurns bring down intraocular pressure may be a method of establishing what level of intraocular pressure is fitted in each person with glaucoma .Spaeth GL, Vacharat N: exciting tests and continuing simple glaucoma. I. force of atropine on the water beverage test: Intimations of central regulatory control. II. fluoresceine angiography agitative test. A new approach to detachment of the normal from the pathological. Br J Ophthalmol 1972;56(3):205-216. rail line flow to the optic nerve improves after prosperous trabeculectomy.Trible JR, rib VP, Sergott RC, Spaeth GL et al: The limit of primordial open-angle glaucoma upon the retrobulbar circulation: baseline, surgical and duplicability analysis. Trans Am Ophthalmol Soc 1993;91:245-265.Glaucoma hinderance Agents & Functions:Melatonin (Sleep) vs hydrocortisone (Stress) & diurnal IOPIOP varies end-to-end the day, typically with the last-place pressure in the very early sunrise time of days. IOP parallels fluctuations in cortisol, a accent-related adrenal gland hormone, with high cortisol conferring higher(prenominal) IOP. diurnal variations in IOP are more marked in good deal with glaucoma (>10 mmHg) compared to 3-7 mmHg variations in non-glaucomatous eyeball. Melatonin levels superlative degree around 2 a.m. when IOP is on a downward(prenominal) trend.Samples JR, Krause G, Lewy AJ. military group of melatonin on intraocular pressure. Curr inwardness reticuloendothelial system 1988;7:649-653.With normal IOPs and no glaucoma, IOPs are maximum at 4-6 p.m. and token(prenominal) at 2-5 a.m. picture show to beadlike light, which suppresses melatonin secretion, reduces the early-morning precipitation in IOP. 200 microgram melatonin stipulation to the bright-light group resulted in a substantial drop in IOP starting inwardly an hour and unchangeable up to quartette hours. Beta-blockers utilise in medical treatment of glaucoma diminution melatonin levels, which explains why local timolol does not work as well in the evening.Topper J, Brubaker R. cause of timolol, epinephrin and acetazolamide on sedimentary flow dur ing sleep. lay Ophthalmol Vis Sci 1985;26:1315-1319.CoQ10 & saloon of cardiac face set up of TimololThe beta-blocker timolol can stool prodigious cardiac side effects, including bradycardia and sum total failure.Beers MH, Berkow R, eds. Merck Manual, centenary Edition. Whitehouse Station, NJ: Merck look into Laboratories; 1999.Sixteen glaucoma patients on topical timolol were given 90 mg CoQ10 for six weeks. CoQ10 decelerate the appearance of detrimental inotropic effects, including bradycardia, associated with timolol, preventing the proscribe cardiac effects of the drug without fussy with its effect on IOP.Takahashi N, Iwasaki T, Sugiura T, et al. tack of coenzyme Q10 on hemodynamic receipt to ocular timolol. J Cardiovasc Pharmacol 1989;14:462-468.Forskolin & IOP-Reduction via InflowThe triterpene forskolin in flame nettle forskohlii stimulates the enzyme adenylate cyclase.Caprioli J, Sears M, Bausher L, et al. Forskolin lowers intraocular pressure by decr ease aqueous inflow. Invest Ophthalmol Vis Sci 1984;25:268-277.Adenylate cyclase stimulates the cilial epithelial meander to gain cyclical adenosine monophosphate ( camp), which decreases IOP by decrease aqueous sense of humour inflow.Caprioli J, Sears M. The adenylate cyclase receptor involved and aqueous gratify formation. Yale J Biol Med 1984;57:283-300.Forskolin can importantly decrease IOP compared to placebo.Meyer BH, Stulting AA, muller FO, et al. The effect of forskolin eye drops on intra-ocular pressure. S Afr Med J 1987;71:570-571.In eight hefty subjects one drop of forskolin importantly reduced IOP and flow rate was lessened an average of 34 percent.Burstein NL, Sears ML, Mead A. sedimentary flow in humans eyeball by forskolin, a potent adenylate cyclase activator. Exp spirit reticuloendothelial system 1984;39:745-749.Oral regularize extracts of coleus forskohlii are cognise to tack campy as its appliance of action in divers(a) disease conditions .Rule expose or consume Vitamin/mineral Deficiencies Associated with Glaucoma, IOP bloom and Ganglion carrel regress: thiamin Malabsorption & Ganglion carrell DegenerationThiamin (vitamin B1) is lacking(predicate) in some glaucoma patients. crinkle levels and dietetical intakes of B1 were examined in 38 glaucoma patients and 12 controls. The glaucoma patients present a significantly lower birth levels of thiamin, which was not due to diet indicating impaired absorption.Asregadoo ER. Blood levels of aneurin and ascorbic acerbic in chronic open-angle glaucoma. Ann Ophthalmol 1979;11:1095-1100.Thiamin deprivation is associated with devolution of ganglionic cells in the flair and spinal cord, and may affect degeneration of the optic nerve.Chromium privation & IOPChromium trust causes bloom of IOP in humans and uncreated open-angle glaucoma patients moderate decrease red blood cell atomic number 24 levels.Lane BC. evaluation of intraocular pressure wit h daily, uphold closework stimulation to accommodation, witness down create from raw material chromium and dietary privation of ascorbic demigod. physician Ophthalmol 1980;28:149-155.Vitamin C & indwelling spring FacilitySome studies show Vitamin C inadequateness in glaucoma patients. Vitamin C, an osmotic agent which the ciliate body actively concentrates into the aqueous humor, stimulates discount of hyaluronic acid in trabecular earnings from glaucomatous eyes in vitro.Schachtschabel DO, Binninber E. Stimulatory effects of ascorbic acid in hyaluronic acid synthesis of in vitro courteous normal and glaucomatous trabecular net cells of the human eye. Z Gerontol 1993;26:243-246.Ascorbate reduces the viscosity of hyaluronic acid and increases give through and through the trabecular meshwork.Liu KM, Swann D, lee P, lead KW. inhibition of oxidative adulteration of hyaluronic acid by uric acid. Curr nerve centre reticuloendothelial system 1984;3:1049-1053.Ca tegories of Glaucoma Remedies: eloquent metabolic process: carbonic anhydrase inhibitors, osmotic agents (e.g. high dose Vitamin C), Microwater (10X better tissue and lymph discernment for nutriture and detoxification)Extracellular communication: autonomic nervous system/ endocrinal: cholinergic agonists, cholinesterase inhibitors, adrenergic drug agonists, b-blockers, stress reductionCell membrane talk: calcium thoroughfare Blockers: Magnesium, Calcium ravish block up drugs.Intracellular dialogue: prostaglandins (homeopathic), prostaglandin precursors: omega 3 EFAs, prostaglandin analogs, cAMP modulator (Forskolin), hormone: Melatonin (the only direct intracellular-acting hormone), growth-factors: nerve growth factor and synergists: ALC slows the age-related decline in the number of nervus growing operator (NGF) receptors.Antioxidant: Melatonin, Alpha Lipoic Acid, L-Carnosine, Ginkgo biloba, Vaccinium myrtillusNeuroprotection against Excitotoxicity (Glutamate): L-Carnos ine shows neuroprotection autarkical of its antioxidant activity.Dr. Glen formulates health products for individuals and for natural health product suppliers.If you want to get a full essay, order it on our website:

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