Atopic Dermatitis

Current management of atopic dermatitis and interruption of the atopic march Mark Boguniewicz, MD,a Lawrence F. Eichenfield, MD,b and doubting Thomas Hultsch, MDc,d Denver, Colo, San Diego, Calif, Mainz, Germany, and atomic number 99 Hanover, NJ Treatment of atopic dermatitis requires a comprehensive approach that includes evaluation of potential drop triggers and discipline of the patient and family regarding halal avoidance measures. Hydration of the skin and livelihood of an built-in skin barrier remain integral to proper management. Although topical corticosteroids have been a mainstay of anti-inflammatory therapy, the newer topical calcineurin inhibitors shot advantages for discourse of this chronic, relapsing disease. Studies aimed at defining optimum confederacy therapy and early intervention might change the treatment epitome for atopic dermatitis. (J Allergy Clin Immunol 2003;112:S140-50.

) Key words: Atopic dermatitis, atopy, asthma, steroids, calcineurin inhibitors Abbreviations used AD: Atopic dermatitis EASI: Eczema part and severity index FTU: Fingertip unit IGA: investigators global assessment NF-ATp: Nuclear factor of actuate T-cell protein PUVA: Psoralen unseeable A-range SCORAD: Scoring atopic dermatitis index As discussed in the hold by Spergel and Paller,1 not only is atopic dermatitis (AD) an increasingly prevalent disease that impacts significantly on the lives of patients and their families, but approximately half of the patients will go on to develop asthma. New insights into the immunopathogenesis of AD as discussed in the obligate by Novak et a l2 will likely yield more than targeted th! erapy not only for AD but with potential to colour the atopic march. At present, management of patients with AD includes avoidance of irritants and specific triggers, reestablish and maintenance of the skin barrier, interruption of the itchscratch cycle, and reduction of inflammation. In this article we review principles of conventional therapy as well as the newer topical...If you lack to get a full essay, order it on our website: OrderCustomPaper.com

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